HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Thomas Helleday Selected Research

Antimetabolites

11/2022Targeting the DNA damage response and repair in cancer through nucleotide metabolism.
10/2021Small molecule inhibitor of OGG1 blocks oxidative DNA damage repair at telomeres and potentiates methotrexate anticancer effects.
6/2017SAMHD1 protects cancer cells from various nucleoside-based antimetabolites.
4/2017dUTPase inhibition augments replication defects of 5-Fluorouracil.
1/2016Targeting DNA repair, DNA metabolism and replication stress as anti-cancer strategies.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown:


Thomas Helleday Research Topics

Disease

98Neoplasms (Cancer)
11/2022 - 08/2002
9Genomic Instability
01/2022 - 05/2005
6Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2022 - 08/2014
6Breast Neoplasms (Breast Cancer)
01/2022 - 01/2011
6Prostatic Neoplasms (Prostate Cancer)
11/2021 - 02/2012
6Fanconi Anemia (Fanconi's Anemia)
01/2020 - 07/2010
6Ataxia Telangiectasia (Louis Bar Syndrome)
12/2012 - 12/2004
5Hypersensitivity (Allergy)
01/2022 - 04/2007
4Hypoxia (Hypoxemia)
11/2021 - 10/2010
4Neoplasm Metastasis (Metastasis)
03/2020 - 10/2010
3Melanoma (Melanoma, Malignant)
01/2022 - 01/2018
3Inflammation (Inflammations)
01/2022 - 01/2017
3Hematologic Neoplasms (Hematological Malignancy)
11/2021 - 11/2010
3Leukemia
10/2020 - 02/2016
3Skin Neoplasms (Skin Cancer)
01/2020 - 01/2010
3Carcinoma (Carcinomatosis)
01/2020 - 04/2014
3Small Cell Lung Carcinoma (Small Cell Lung Cancer)
01/2019 - 05/2003
3Carcinogenesis
12/2014 - 01/2005
3Chromosome Aberrations (Chromosome Abnormalities)
06/2014 - 12/2006
2Disease Progression
01/2022 - 01/2017
2Poisoning
01/2020 - 10/2015
2Ovarian Neoplasms (Ovarian Cancer)
01/2019 - 08/2009
2Cockayne Syndrome (Syndrome, Cockayne)
10/2018 - 11/2010
2Premature Aging
12/2014 - 07/2007
1Autoimmune Diseases (Autoimmune Disease)
01/2022
1Multiple Sclerosis
01/2022
1Hepatitis
01/2022
1Triple Negative Breast Neoplasms
01/2022
1Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
01/2022
1Liver Diseases (Liver Disease)
01/2022
1Autoimmune Hepatitis
01/2022
1Infections
12/2021
1Leukopenia
01/2021
1Lymphoma (Lymphomas)
01/2021
1Neuroblastoma
01/2021
1Psoriasis (Pustulosis Palmaris et Plantaris)
01/2021
1B-Cell Lymphoma (Lymphoma, B Cell)
01/2021
1Osteosarcoma (Osteogenic Sarcoma)
03/2020

Drug/Important Bio-Agent (IBA)

37DNA (Deoxyribonucleic Acid)IBA
11/2022 - 09/2002
27Proteins (Proteins, Gene)FDA Link
01/2022 - 06/2008
16EnzymesIBA
11/2022 - 01/2005
15NucleotidesIBA
11/2022 - 01/2005
11karonudibIBA
01/2022 - 01/2018
8Pharmaceutical PreparationsIBA
01/2022 - 01/2017
8Reactive Oxygen Species (Oxygen Radicals)IBA
01/2022 - 04/2014
8Poly(ADP-ribose) Polymerase InhibitorsIBA
01/2020 - 06/2010
7Phosphotransferases (Kinase)IBA
01/2017 - 12/2004
5AntimetabolitesIBA
11/2022 - 01/2016
5NucleosidesIBA
06/2017 - 10/2015
51,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA
11/2015 - 05/2003
5Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
12/2012 - 09/2005
4Cytarabine (Cytosar-U)FDA LinkGeneric
01/2020 - 01/2017
4A-Form DNA (A-DNA)IBA
10/2018 - 04/2005
4Biological ProductsIBA
01/2018 - 12/2006
4Histones (Histone)IBA
01/2018 - 06/2014
3ThymidineIBA
01/2022 - 01/2004
3AntioxidantsIBA
11/2021 - 01/2016
3Small Interfering RNA (siRNA)IBA
12/2020 - 04/2010
3Messenger RNA (mRNA)IBA
01/2020 - 02/2012
3dCTP pyrophosphataseIBA
01/2017 - 02/2016
3Androgen Receptors (Androgen Receptor)IBA
01/2017 - 03/2013
3Checkpoint Kinase 1IBA
12/2016 - 05/2005
3DNA-Directed DNA Polymerase (Polymerases, DNA)IBA
11/2012 - 01/2005
2Methylenetetrahydrofolate Dehydrogenase (NADP) (Dehydrogenase, Methylenetetrahydrofolate)IBA
01/2022 - 01/2022
2TH5487IBA
01/2022 - 10/2021
22-mercaptopurineIBA
01/2021 - 10/2020
28-oxodeoxyguanosine triphosphateIBA
01/2021 - 08/2015
2Nudix HydrolasesIBA
10/2020 - 11/2017
2ProteomeIBA
01/2020 - 01/2017
2purineIBA
01/2020 - 01/2017
2DeoxycytidineIBA
01/2020 - 02/2017
2Hormones (Hormone)IBA
11/2019 - 01/2018
2STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
10/2018 - 01/2017
2Biomarkers (Surrogate Marker)IBA
01/2018 - 02/2012
2AndrogensIBA
01/2017 - 03/2012
2CrizotinibIBA
01/2017 - 04/2014
2Thioguanine (Tioguanine)FDA Link
01/2016 - 08/2010
2DecitabineFDA Link
08/2014 - 06/2013
2CamptothecinIBA
06/2014 - 09/2008
2Alkylating AgentsIBA
05/2011 - 09/2010
2Etoposide (VP 16)FDA LinkGeneric
07/2003 - 05/2003
1AntigensIBA
01/2022
1Folic Acid (Vitamin M)FDA LinkGeneric
01/2022
1olaparibIBA
01/2022
1Concanavalin AIBA
01/2022
1Therapeutic UsesIBA
01/2022
1Ganciclovir (Cytovene)FDA LinkGeneric
12/2021
1Antineoplastic Agents (Antineoplastics)IBA
11/2021
1Glutathione (Reduced Glutathione)IBA
11/2021
1piperlongumineIBA
11/2021
1Methotrexate (Mexate)FDA LinkGeneric
10/2021
1AdenineFDA LinkGeneric
01/2021
1CytosineIBA
01/2021
1Imiquimod (Aldara)FDA LinkGeneric
01/2021
1Gefitinib (Iressa)FDA Link
01/2020

Therapy/Procedure

39Therapeutics
01/2022 - 07/2003
14Drug Therapy (Chemotherapy)
11/2022 - 05/2009
9Radiotherapy
01/2022 - 04/2010
5Castration
11/2021 - 03/2012
1Immunotherapy
01/2021